Resveratrol/chemoprevention
Resveratrol/chemoprevention
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Cancer chemopreventive activity of resveratrol, a natural product derived from grapes
Cancer chemopreventive activity of resveratrol, a natural product derived from grapes
Antioxidant, antimutagen
Anti-carcinogenesis activity: anti-initiation, antipromotion and anti-progression
Present in human diet; potential cancer-preventive agent
Published date: 1997 Jan
Journal: Science
Citation by (up to 6/2025): 6983
Link: https://pubmed.ncbi.nlm.nih.gov/8985016/
The identification of NQO2 as resveratrol target protein
The identification of NQO2 as resveratrol target protein
Crystal structure of quinone reductase 2 in complex with resveratrol
Crystal structure of quinone reductase 2 in complex with resveratrol
Potent inhibitor of NQO2/QR2 activity with a dissociation constant of 35 nM
Binding affinity suggests potential interaction with other polyphenols like quercetin
Implication: Resveratrol's benefits may stem from NQO2/QR2 inhibition, leading to increased cellular resistance to oxidative stress
Published date: 2004 Sep
Journal: Biochemistry
Citation (up to 6/2025): 289
Citation (up to 6/2025): 289
Link: https://pubmed.ncbi.nlm.nih.gov/15350128/
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"While the publications listed above establish the foundational biochemical framework for NQO2 and Resveratrol, the field is rapidly evolving. We provide real-time updates, newly published PubMed abstracts, and technical summaries as they emerge. To view the latest developments in NQO2 redox regulation and stilbene research, visit our [Latest Updates] (link to New Sharing page) section."
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